Induced host resistance to a transplantable mouse glioma.

A transplantable methylcholanthrene-induced glioma has been carried by subcu taneous transplantation in inbred C57/6 mice and grows rapidly within 3-4 weeks in almost all recipients. Immunization with glioma-adjuvant mixture resulted in inhibi tion or "rejection" of 70 per cent of tumor implants given later, whereas immunization with spleen-adjuvant, brain-adjuvant mixtures, or adjuvant alone resulted in in hibition or "rejection" of only 4 per cent of later tumor implants. The previous work on